Late potentials and the Brugada syndrome.
نویسنده
چکیده
The Brugada syndrome accounts for approximately 20% of cases of sudden cardiac death in patients with structurally normal hearts (1–3). The syndrome is characterized by an ST-segment elevation in right precordial leads (V1 to V3) unrelated to ischemia, electrolyte disturbances or obvious structural heart disease, and is sometimes accompanied by a right bundle branch block (RBBB) morphology of the QRS. This electrocardiographic (ECG) signature was reported as early as 1953, but it was first described as a distinct clinical entity associated with a high risk of sudden cardiac death by Pedro and Josep Brugada in 1992 (4). These characteristics of the Brugada syndrome are similar to those reported by Nademanee et al. (5) for patients with sudden unexplained death syndrome, and recent study has advanced data suggesting the two syndromes are genetically and functionally the same disorder (6).
منابع مشابه
Comparison of Late Potentials for 24 Hours between Brugada Syndrome and Arrhythmogenic Right Ventricular Cardiomyopathy Using a Novel Signal-Averaging System Based on Holter Electrocardiogram Running title: Abe et al.; Comparison of LPs for Brugada syndrome and ARVC
متن کامل
Human ventricular action potential duration restitution.
. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden death: a distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol 1992;20:1391–6. . Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 1999;100:1660–6. . Breithardt G, Cain ME, El-Sheri...
متن کاملBrugada Syndrome Manifested by the Typical Electrocardiographic Pattern both in the Right Precordial and the High Lateral Leads
We identified a patient with the Brugada syndrome and frequent episodes of the traumatic syncope. This patient presented with alternating ST-segment elevation in the right precordial and the high lateral leads. The signal-averaged ECG was positive for the late potentials and electrophysiology study revealed no inducible supraventricular or ventricular tachycardias. Because of the frequent traum...
متن کاملBasis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome
AIMS Human action potentials in the Brugada syndrome have been characterized by delayed or even complete loss of dome formation, especially in the right ventricular epicardial layers. Such a repolarization pattern is believed to trigger phase-2 reentry (P2R); however, little is known about the conditions necessary for its initiation. This study aims to determine the specific mechanisms that fac...
متن کاملA case of Brugada Syndrome unmasked by a postoperative febrile state
Abstract Background: Brugada Syndrome (BS) is an inherited ion channelopathy characterized by an electrocardiographic (ECG) pattern of a coved type ST segment elevation in right precordial leads with or without right bundle branch block. Case Presentation: A 23-year old male presented with right lower quadrant abdominal pain. Further evaluation revealed a diagnosis of acute appendicitis. The ...
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ورودعنوان ژورنال:
- Journal of the American College of Cardiology
دوره 39 12 شماره
صفحات -
تاریخ انتشار 2002